Stem Cell Injections - MY CONCIERGE MD

Stem cell therapy is an exciting and promising new treatment for a variety of diseases and injuries. It has the potential to help treat a range of conditions, from osteoarthritis to spinal cord injuries, as well as a number of other medical issues. While research is still ongoing, initial studies have been very promising, and the potential of stem cell therapy is certainly worth keeping an eye on.

It is important to note that at the current time, Stem Cell therapies including IV therapy and injections are not FDA approved for therapy for any medical conditions.

Stem cell-based therapies and PRP therapies are offered as part of regenerative medicine therapies. Stem cell therapies derived from fat, bone marrow, and umbilical cord, as well as platelet-rich plasma therapy, are ongoing research and clinical trials but have been used for the treatment of the following medical conditions;

  • Hair loss
  • Facial rejuvenation
  • Tendonitis, such as seen in golfers’ elbow and tennis elbow
  • Knee pain
  • Joint pain
  • Shoulder pain
  • Osteoarthritis
  • Articular cartilage injury
  • Meniscus injury
  • Rotator Cuff injury
  • Fracture non-unions
  • Avascular necrosis
  • Wound healing
  • Erectile dysfunction

Stem cell treatments and PRP therapies aim to regenerate and alleviate pain caused by sporting activities and recreational exercisers, as well as seniors who are afflicted with wear-and-tear injuries or degenerative arthritis. Through stem cell therapy, individuals seeking relief from painful conditions can receive effective treatment at an expedited pace without the need for invasive procedures.

Contact us today to schedule your consultation with one of our healthcare providers to learn more about the treatments offered and available to you.

What are stem cells?

According to the National Institute of Health (NIH), stem cells are special cells that can differentiate into the various tissues in our bodies, such as muscle tissue, nerves, skin, and blood. They also have a crucial role during fetal development by acting as the fundamental cell types for all body systems – from the formation of tissues like fleshy and bone-like masses to replenishing dying organs until they eventually yield fresh ones again.

There are several types of stem cells, including adult stem cells, which can be found in the body and can continue to divide; embryonic stem cells, which are found in the early stages of development and can only divide a limited number of times; and induced pluripotent stem cells (iPSCs), which are created from mature skin cells that have been turned into pluripotent stem cells.

Types of stem cells

Mesenchymal Stem Cells (MSCs)

Mesenchymal stem cells are adult stem cells extracted from a range of sources, such as bone marrow, adipose tissue (fat), umbilical cord tissue, and even amniotic fluid surrounding a fetus. Differentiation potential is exhibited by these adult progenitor cells that can be used therapeutically for regenerative purposes.

MSCs are found in every person’s bone marrow and accumulate during youth for eventual use to support the body’s healing process. As we age, however, their number and efficacy dwindle – a phenomenon commonly observed among all human life spans.

Mesenchymal stem cells (MSCs), or stromal stem cells, can differentiate into a plethora of cellular fusions within the body; these include:

  • Skin cells
  • Bone cells
  • Cartilage
  • Muscle cells
  • Neural cells
  • Corneal cells

The most concentrated source for Mesenchymal stem cells is the adult bone marrow. Adipose tissue and fetal bovine serum are other sources for extracting and concentrating Mesenchymal stem cells. There are currently many studies investigating the usefulness and benefits of these cells in the treatment of a variety of illnesses and diseases. Mesenchymal stem cells can be expanded and replicated in vitro to achieve higher amounts of cells to be used in clinical doses. Culture conditions have an impact on the efficacy and usefulness of these regenerative cells. These regenerative cells can be injected or infused intravenously depending on the clinical treatment.

Extracellular vesicles also called ( EV’s) include exosomes, microvesicles and apoptotic bodies that are further released by stem cells and are thought to have therapeutic potential.

Stem Cell Therapy and Long Covid

Infection with COVID-19 has shown to have caused organ tissue damage such as lung and heart damage causing palpitations and shortness of breath. Patients showing signs of long COVID may have heart palpitations and shortness of breath [1].

In addition, studies have shown excessive inflammation and a hyperactive immune response with elevated inflammatory markers and cytokine levels in patients suffering from long COVID [1]

Elevated systemic inflammation can cause a disruption in the blood brain barrier that can attribute to brain fog and cognitive decline [2]. Stem cell therapy and its ability to possibly treat these conditions has gained popularity and is actively being studies due to its potential benefits

Mesenchymal Stem cells have the potential to heal and repair tissues and organs via replacement of damaged cells or repair. They are also thought to help in the regulation of the excessive inflammatory response associated with long COVID. [3]

Autogenous MSCs & Autologous MSCs

Autogenous MSCs are typically derived from a patient’s own bone marrow or fat. Current scientific evidence supports the greatest benefit of stem cells extracted from bone marrow aspirate concentrate (BMAC), making it doctors’ preferred option for treatment and regeneration. On the other hand, additional stem cell research into functionalities, regenerative capacities as well as alleviating pain associated with those sources of MSCs is currently underway.

MSCs have been shown to promote regeneration and wound healing, as well as combat inflammation. In fact, MSCs have been found to improve outcomes in a wide variety of chronic diseases, including osteoarthritis, multiple sclerosis, rheumatoid arthritis, and spinal cord injury.

Allogeneic MSCs

Allogenic MSCs, or allogeneic mesenchymal stem cells, are a type of stem cell therapy that is gaining traction in the medical world. This type of stem cell therapy is unique because it uses stem cells taken from a donor and transplanted into the patient, allowing the patient to reap the benefits of the donor’s healthy cells. By doing this, researchers are able to use fewer stem cells than traditional therapies and still achieve great results. Allogenic MSCs have been shown to help with a variety of ailments and diseases, making them a promising treatment option for many.

Umbilical Cord Blood

Umbilical cord blood is a rich source of stem cells, which can be used for a variety of medical therapies. These stem cells have the ability to differentiate into various types of cells, including blood cells and immune cells. This property makes them useful for treating a wide range of diseases, such as blood cancers like leukemia and lymphoma, inherited immune system and metabolic disorders, and inherited blood disorders such as sickle cell anemia and thalassemia.

Umbilical cord blood stem cells are also being studied and used for their potential use in regenerative medicine. The procedure is relatively non-invasive, and it is easy to collect and process cord blood.

Cord blood banking is the process of collecting and storing umbilical cord blood for future medical use. Cord blood can be collected and stored at a cord blood bank, either privately or through the public cord blood donation program, in case the baby or family member may need it in the future.

What do stem cell injections do?

Stem cell therapy is a promising medical treatment that uses the self-renewal, immunomodulatory, and anti-inflammatory properties of stem cells to alter the physiology within the human body positively.

The stem cells used in the injections can either be taken from the patient’s own body or from a donor. The stem cells are then injected directly into the affected area, which repair and regenerate damaged tissue.

Injecting stem cells can help reduce inflammation, improve mobility, and even reduce pain. While stem cell therapy is still considered very new, it is showing promising results for many patients. If you are interested in exploring this option further, be sure to speak with your healthcare provider.

What can be the benefits of stem cell injections?

1. Cardiovascular Disease Treatment

According to clinical research being currently performed, stem cell therapy is an emerging and promising treatment for cardiovascular diseases. It involves injecting fresh stem cells into the affected area to improve cardiovascular function and regenerate healthy tissue. This therapy has been utilized to treat various conditions, including heart attacks and strokes, and shows great potential in cardiac regeneration and repair.

Since the first transplant into human patients, different types of stem cells, such as bone marrow-derived stem cells and embryonic stem cells, have been used in this field. The goal of stem cell therapy is to transplant enough cells into the myocardium at the site of injury or infarction to maximize the restoration of function.

2. Treatment of Neurodegenerative Diseases

Stem cell therapy is a promising new treatment for neurodegenerative diseases such as Huntington’s and Parkinson’s diseases. To slow or reverse the progression of the disease, a stem may be used to replace damaged cells. Recent clinical trials have been encouraging, providing evidence that stems cell therapy could be a viable option for treating these devastating illnesses.

3. Wound Healing

Research suggests that it can also help heal incisions and wounds. Stem cell therapy is gaining traction in the medical community as an effective way to help speed up the healing process of a patient post-surgery or other injuries. With the ability to jump-start the healing process, stem cell therapy offers patients a new option for faster recovery.

4. Orthopedic Conditions

Studies also show the potential for stem cells to help heal and regenerate damaged tissue. These treatments are becoming more available to patients with osteoarthritis, tendonitis, and ligament injuries. While there is still much to learn about the full capabilities of stem cell therapy, growing evidence suggests that it can be an effective treatment for many orthopedic issues.

5. Autoimmune Diseases

Autoimmune diseases occur when the body’s own immune system attacks healthy tissue. This can cause conditions like lupus, multiple sclerosis, rheumatoid arthritis, and Crohn’s disease. Stem cell therapy may reduce inflammation and stop the immune system from attacking its own cells.

STEM CELL AND REGENERATIVE TREATMENTS

Stem cell injections can be administered in conjunction with one’s surgical treatment, augmenting its effects or utilized as a solitary therapy for alleviating pain related to orthopedic conditions. Many patients who seek relief from excruciating joint issues opt to try this form of regenerative medicine in order to forego surgery altogether; success may often be attained through concomitant utilization of stem cells along with the procedure itself. By reducing infection risk and ameliorating postoperative inflammation, restoration time is shortened while also enhancing faster healing times and ultimately hastening return-to-normality after surgeries – all without any additional expenditure!

Stem cell injections can be augmented by conjoining them with other orthobiologic modalities like prolotherapy or PRP injection of the dextrose-saline solution. Platelets are believed to be home to myriad growth factors and cytokines which may aid in tissue regeneration; consequently, incorporating stem cells into the mix might generate an even more intense healing response.

WHAT CONDITIONS CAN STEM CELL THERAPY TREAT?

Stem Cells For Hair Loss

In order for stem cell therapy to work, stem cells from another part of the body must be transplanted into the scalp. This may encourage the growth of new hair and regenerate lost hair follicles. The procedure has shown promising results in some studies, despite being in its early stages.

Stem Cells For Hair Loss - MY CONCIERGE MD

Stem Cells for Facial Rejuvenation

With this groundbreaking new method, stem cells are used to effectively minimize lines and wrinkles, enhance skin tone, and even promote the production of collagen. You can look younger without invasive surgery or pricey creams by using this natural method that is both safe and effective. For facial rejuvenation, microneedling is frequently combined with stem cell therapy and PRP therapy.

Stem Cells for Erectile Dysfunction

A fascinating new treatment for erectile dysfunction in men is stem cell therapy. Men may experience better circulation and erectile function after receiving stem cell injections into the penis. Injections of stem cells into the corpus cavernosum of the penis are used in stem cell therapy for ED to improve erection quality and speed up tissue repair. Even though the therapy is still in its early stages, many men have already experienced success with it. As stem cell therapy develops, it might become a promising new treatment for erectile dysfunction.

Stem Cells for Dark Under Eyes

Stem cell therapy is helping people reduce their under-eye bags and dark circles without needing makeup or invasive surgeries. By using stem cells, people can now improve their skin tone and reduce wrinkles around their eyes. With this safe and effective therapy, people can look more rested and refreshed without having to resort to drastic measures. Our clinic provides stem cell and PRP therapy with micro-needling for the treatment of dark under the eyes.

Stem Cells for Wound Healing

Mesenchymal stem cells (MSCs) can be used to promote the growth of new blood vessels in the wound, which can improve blood flow and oxygenation to the area and speed up the healing process.

Additionally, MSCs can also differentiate into cells that produce collagen, a protein vital for the formation of new tissue. This can help to strengthen the wound and improve its overall appearance.

There are various kinds of stem cells with various characteristics. One of the most studied Stem cells for wound healing is the Adult Stem cells which can be obtained from many different sources such as fat, bone marrow, and skin. They can be used to help heal chronic wounds such as those caused by diabetes and the healing of burn injuries.

Stem Cell Therapy For Musculoskeletal Conditions

Bone Repair

Recent studies have shown that stem cell injections directly into damaged bones can lead to the regeneration of new, healthy tissue. This could provide an alternative treatment to traditional bone repairs techniques such as surgery or splints.

Ligament and Tendon Repair

Physicians’ approaches to tendon and ligament repair are being revolutionized by stem cell therapy. These soft tissues can now be repaired by doctors in a much less invasive way by using stem cell therapies. It has been demonstrated that stem cell therapy shortens hospital stays and enhances patient outcomes.

Joint Repair

Those who suffer from joint pain may find relief with stem cell therapy. During this procedure, stem cells are injected into the damaged area to help with the promotion of healing and repair. Many patients now experience less pain and can move more freely thanks to this technology. Although stem cell therapy is still relatively new, it is rapidly developing into a viable option for those seeking relief from joint pain.

Muscle Repair

In stem cell therapy, the affected muscle receives a direct injection of stem cells. The ability of these stem cells to differentiate into new cells can then help repair and rebuild damaged muscle tissue. Stem cell therapy may eventually be used to treat paralysis brought on by traumatic spinal cord injuries. This depends on how much more research is done in this area.

Articular Cartilage Injury

Recent research suggests that the treatment can help promote tissue growth and regeneration, which can improve joint function in addition to reducing pain and inflammation. This offers hope to people who have been dealing with chronic joint problems that have resisted conventional medical interventions.

Meniscus Repair

Due to the regenerative abilities of stem cells, they are a promising new treatment for meniscal or meniscus injuries. In order to repair the meniscus naturally and minimally invasively without resorting to open surgery involves using the patient’s own stem cells to regenerate the damaged tissue in the knee. This might offer a wonderful alternative to surgery while still delivering successful and long-lasting results.

Rotator Cuff Repair

Stem cell therapy is a type of regenerative medicine that involves using stem cells or their derivatives to promote the repair response of diseased, dysfunctional, or injured tissue. Researchers grow stem cells in a lab, which can be used to help repair torn or otherwise damaged rotator cuff muscles.

Stem cells are part of the body’s natural repair process, and when they are placed at the site of damaged tissue, they can activate and become the healthy new cells the body needs. Stem cell therapy has been around since the 1970s and has the potential to revolutionize the way rotator cuff injuries are treated.

Patients who have undergone this therapy have reported improved mobility and less pain in their shoulder joints. With the ability to repair tissue and relieve pain, stem cell therapy is an exciting and promising development.

Fracture Non-unions

Traditional surgical approaches have been less effective compared to stem cell therapy. Stem cells are injected into the bone to promote the growth of new bone and facilitate healing. Improved success rates, reduced patient morbidity, quicker recovery times, and potentially reduced cost of managing non-union are among the expected benefits of stem cell therapy.

Avascular Necrosis

Avascular necrosis is a painful bone condition that develops when blood flow to a portion of bone is cut off, resulting in the death of the bone tissue and ultimately leading to the collapse of the affected bone. This may occur as a result of radiation therapy, alcohol abuse, a broken bone or dislocated joint, or other conditions that affect blood flow.

Stem cell therapy has emerged as an exciting new treatment option for avascular necrosis, even though surgical interventions are frequently necessary to treat the symptoms of the condition. Stem cells can be injected directly into the injured area, where they help to dissolve dead bone and regenerate tissue, relieving the pain and averting further damage.

What are the dangers of injecting stem cells?

Patients may suffer from short-term side effects such as –

  • Infections
  • Bleeding or bruising
  • Nerve inflammation
  • Tissue pain
  • Reactions at the site of collection and administration

Stem Cell Transplantation

Stem cell transplantation is a medical procedure in which stem cells, typically from the bone marrow, are transplanted into a patient’s body to replace damaged or destroyed cells. The stem cells used for transplantation can come from a number of sources, including the patient’s own body (autologous transplantation), a matched donor (allogeneic transplantation), or umbilical cord blood.

The most common type of stem cell transplantation is bone marrow transplantation, which is used to treat blood cancers such as leukemia, lymphoma, and multiple myeloma, as well as the certain inherited immune system and metabolic disorders. The procedure involves destroying the patient’s diseased bone marrow with chemotherapy and/or radiation and then transplanting healthy stem cells to repopulate the bone marrow and restore the patient’s ability to produce blood cells.

Stem cell transplantation can also be used to treat other conditions, such as inherited blood disorders, autoimmune disorders, and some solid tumors. Stem cell transplants are usually considered when other treatments have failed or when the patient has a high risk of relapse after other treatments.

Stem Cell Therapy & the FDA

Many stem cell therapies are in ongoing clinical trials and have yet to be approved by the FDA and should be administered through investigational new drug applications. Our healthcare providers can consult with you and guide you through the different treatment options that are approved and can be safely performed. We look forward to having a consultation with you.

 

References

  1. Post-Covid Conditions, Centers for Disease Control and Prevention, Centers for Disease Control and Prevention, https://www.cdc.gov/coronavirus/2019-ncov/long-term-effects/index.html.

  2. Greene, C., Connolly, R., Brennan, D. et al. Blood-brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairment. Nat Neurosci 27, 421–432 (2024). https://doi.org/10.1038/s41593-024-01576-9

  3. Mesenchymal Stem Cell, Mesenchymal Stem Cell – an Overview | ScienceDirect Topics, https://www.sciencedirect.com/topics/engineering/mesenchymal-stem-cell.

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