Tirzepatide can cause the pancreas to produce insulin in response to meal intake while decreasing the liver’s glucagon synthesis. It can help in weight loss in patients with obesity or overweight issues. At My Concierge MD, we will recommend our patients Tirzepatide for weight loss depending on their medical history. There are many options for weight loss medications you can explore. So, schedule a consultation with us.
What is Tirzepatide?
Tirzepatide is a synthetically made drug used to treat type 2 diabetes. It is the first drug that is made from glucose-dependent insulinotropic polypeptide (GIP) receptor and glucagon-like peptide-1 (GLP-1) receptor agonist, which are used to treat type 2 diabetes mellitus as a single therapy or with other diabetes medicines [1]. Still, it is not approved for treating type-1 diabetes mellitus and has not been studied in patients with pancreatitis. Tirzepatide is also known as Mounjaro.
Is tirzepatide available for weight loss?
Yes. Tirzepatide can be used for weight loss effectively in adults with obesity. It works by decreasing appetite and slowing down food digestion and absorption, making you feel full more quickly and for a long time.
A study conducted with participants with obesity issues stated that treatment with tirzepatide had an average weight loss of 10%-20% of their body weight after 72 weeks [2].
What class of drug is tirzepatide?
Tirzepatide is an incretin mimetic drug. It contains both GIP and GLP-1 hormones. And because tirzepatide contains both the incretin hormones (stimulates beta cells in the pancreas to release insulin), they are called also called Twincretin [3].
Who cannot take tirzepatide?
You should not use tirzepatide if you are allergic to it, or if you have a personal or family history of medullary thyroid carcinoma (a type of thyroid cancer), or multiple endocrine neoplasia type 2 (tumors in your glands). Tirzepatide is an incretin mimetic drug and a dual glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) receptor agonist 2
If you’re allergic to tirzepatide or you have a family history of thyroid cancer, it’s best to avoid taking tirzepatide. Patients with tumors in glands should also avoid taking tirzepatide.
Is tirzepatide the same as Ozempic?
No, tirzepatide and ozempic are not the same drugs. While Ozempic is a GLP-1 receptor agonist used for treating type 2 diabetes, Tirzepatide is a dual GLP-1 and GIP receptor agonist that improves blood sugar levels and also decreases appetite.
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How much does tirzepatide cost?
According to Drugs.com, the cost for Tirzepatide subcutaneous solution (2.5 mg/0.5 mL) is around $1,135 for a supply of 2 milliliters. However, you can save on your prescription by using a savings card, a 90-day supply, or a manufacturer coupon.
Is tirzepatide bad for the kidneys?
A study concluded that Tirzepatide may help protect the kidneys in people with type 2 diabetes [4]. It helps slow down the decline of kidney function (eGFR) and prevents the growth of protein in the urine, called microalbuminuria. This helps people with chronic kidney disease or those at a high risk of heart disease.
How effective is Mounjaro for weight loss?
Clinical trials suggest that Mounjaro is somewhat effective in causing weight loss in people who take it. A study conducted by Eli Lilly amongst participants achieved a total average weight loss of 26.6% over 84 weeks.
Another Cleveland Clinic study showed that 2500 obese adults taking 5 mg of Mounjaro for 72 weeks lost 15% of their body weight [5].
Side effects of Mounjaro
Abdominal pain or discomfort
Constipation
Decreased appetite
Diarrhea
Nausea and vomiting
More serious side effects include:
Acute gallbladder disease
Acute kidney injury
Hypoglycemia
Gastroparesis
Pancreatitis
Vision changes
How quickly do you lose weight on tirzepatide?
A study suggested that people who kept taking tirzepatide for 72 weeks (a year and a half) lost 15% of their body weight on average. The duration depends on various pointers like age, gender, diet, lifestyle choice, etc.
Can I get tirzepatide without diabetes?
Yes, Tirzepatide can be used for weight loss in adults with obesity or type 2 diabetes.
How long can you take tirzepatide?
According to Mayo Clinic, the usual adult dose for Tirzepatide is 2.5 mg subcutaneously once a week for the first 4 weeks. After 4 weeks, the dosage should be increased to 5 mg subcutaneously once a week. For additional glycemic control, the dosage can be increased in 2.5 mg increments after at least 4 weeks on the current dose.
Tirzepatide For Weight Loss
My Concierge MD offers the best Tirzepatide for weight loss near me in Beverly Hills but can also come to your home or office throughout the Los Angeles area. We serve patients near Beverly Hills, Bel Air, West Hollywood, Santa Monica, West Los Angeles, Culver City, Hollywood, Venice, Marina del Rey, Malibu, Manhattan Beach, Redondo Beach, Downtown Los Angeles, Encino, Woodland Hills, Sherman Oaks, Calabasas, Burbank, Glendale, Hidden Hills, Agoura Hills, Northridge, North Hollywood, Topanga, Canoga Park, Reseda, Valley Glen, Chatsworth, West Hills, Winnetka, Universal City, Silverlake, Echo Park, and many more.
Jastreboff AM, Aronne LJ, Ahmad NN, et al. Tirzepatide Once Weekly for the Treatment of Obesity. The New England Journal of Medicine. 2022;387(3):205-216. doi:https://doi.org/10.1056/nejmoa2206038
Catalina Bosch, Sol Carriazo, María José Soler, Alberto Ortiz, Beatriz Fernandez-Fernandez, Tirzepatide and prevention of chronic kidney disease, Clinical Kidney Journal, Volume 16, Issue 5, June 2023, Pages 797–808, https://doi.org/10.1093/ckj/sfac274
Jastreboff AM, Aronne LJ, Ahmad N, et al. Tirzepatide Once Weekly for the Treatment of Obesity. The New England Journal of Medicine. 2022;387(3):205-216. doi:https://doi.org/10.1056/nejmoa2206038
Board Certified in Internal Medicine and Specialist in Concierge Medicine & Executive Health. Dr. Nazarian practices Integrative Medicine with focus on preventative medicine, anti-aging, hormone replacement therapy and IV Vitamin optimizations. Dr. David Nazarian, received his bachelor of sciences from the University of Los Angeles, California in Psychology and Biology. He obtained his Medical Doctorate degree from Sackler School of Medicine. He completed his medical residency at Huntington Memorial Hospital, a University of Southern California affiliate hospital. Once completed, he established a practice in the heart of Beverly Hills. Dr. Nazarian is a Diplomat of the American Board of Internal Medicine. He has received numerous awards and recognition as a top doctor in his field.
