Maintaining the proper balance of iron is crucial for normal physiological functioning, as it is an essential element. Iron deficiency is commonly caused by blood loss, which is prevalent among individuals such as females with menstruation and patients with chronic occult gastrointestinal (GI) blood loss. Therefore, accurate diagnosis and appropriate management are necessary [1].
Iron deficiency anemia is a common and clinically important concern in patients with chronic kidney disease (CKD). CKD patients on ESA treatment often develop iron deficiency due to increased demand for erythropoiesis (red blood cell production) support, leading to hypo-responsiveness to ESA therapy, especially in dialysis patients. As a result, iron therapy has been an important component of the management of anemia in patients with CKD for many years [2].
At My Concierge MD, we offer parenteral iron therapy to patients who have been diagnosed with iron deficiency anemia and have not responded well to other forms of treatment. Our team of healthcare professionals works closely with each patient with low iron to develop a personalized treatment plan based on their individual needs and medical history.
Our goal is to help patients achieve optimal iron levels and improve their overall health and well-being. We provide ongoing support and follow-up care to ensure that patients are receiving the best possible treatment for their condition.
Types of anemia
Anemia is a medical condition that occurs when the body does not have enough red blood cells or hemoglobin to carry sufficient oxygen to the body’s tissues. There are several types of anemia, each with its own causes and characteristics. Some common types of anemia include:
Iron-deficiency anemia: The most common type of anemia, caused by a lack of iron in the body, which is necessary for producing hemoglobin.
Vitamin-deficiency anemia: This type of anemia is caused by a lack of certain vitamins, such as vitamin B12 or folic acid, which are essential for red blood cell production.
Aplastic anemia: A rare and potentially life-threatening type of anemia in which the bone marrow does not produce enough red blood cells.
Hemolytic anemia: A type of anemia in which red blood cells are destroyed faster than they can be replaced, leading to a shortage of red blood cells.
Sickle cell anemia: A genetic disorder in which red blood cells are shaped like crescents rather than the normal disc shape, leading to a shortage of red blood cells and a range of health problems.
Thalassemia: A genetic disorder that affects the body’s ability to produce hemoglobin, leading to a shortage of red blood cells and a range of health problems.
Anemia of chronic disease: A type of anemia that can develop as a result of chronic inflammation, infection, or other medical conditions and syndromes.
Symptoms of anemia
Symptoms of anemia can vary depending on the severity of the condition, but some common signs and symptoms include the following:
Fatigue and weakness
Shortness of breath or difficulty breathing
Dizziness or lightheadedness
Pale skin
Headache
Cold hands and feet
Chest pain or an irregular heartbeat
Difficulty concentrating or confusion
Cravings for ice or other non-food items (pica)
Brittle nails or hair loss
What is an iron infusion?
Iron infusion is a medical treatment in which iron is administered directly into a patient’s bloodstream through a vein using an intravenous (IV) drip. This method is used to treat iron deficiency anemia, a condition in which the body lacks a sufficient amount of iron to produce enough hemoglobin, the protein that carries oxygen in the blood.
Iron infusion is often recommended when oral iron supplements are ineffective, cannot be tolerated due to side effects, or are not suitable for the patient’s medical condition. The infusion process typically takes place in a medical setting, such as a hospital or clinic, and is usually administered by a healthcare professional.
Types of iron infusion
There are several types of IV Iron that can be used to treat iron deficiency anemia. These include:
Iron Dextran: This type of iron infusion is given in a single high dose, which can rapidly restore iron levels. However, dextran-containing intravenous iron preparations are associated with an elevated risk of anaphylactic reactions [3].
Iron Sucrose (Venofer): This is a common form of iron infusion that is given in small test doses over a series of treatments. It is generally well-tolerated and has a lower risk of serious side effects compared to other forms of iron injections.
Ferric carboxymaltose: This form of iron infusion is given in a larger dose than iron sucrose and can provide a more rapid increase in iron levels. It is typically given as a single infusion and may require longer monitoring for potential side effects.
Ferumoxytol: This is a newer form of iron infusion that can be given in a single dose and may be better tolerated than other forms of iron infusion. However, it is more expensive than other options and may not be covered by all insurance plans.
Iron Isomaltoside: This is another form of iron infusion that can be used to treat iron deficiency anemia. It is given in a single dose and has been shown to be effective in rapidly restoring iron levels. It also has a low risk of serious side effects. Like Ferumoxytol, it may be more expensive than other forms of iron infusion and may not be covered by all insurance plans.
The four non-dextran formulations (ferric carboxymaltose, iron sucrose, iron isomaltoside, and ferumoxytol) share an equal or near-equal efficacy and safety profile [4].
The choice of iron infusion depends on the patient’s individual needs, medical history, and the severity of their iron deficiency anemia. The healthcare provider will determine the best option for each patient based on these factors.
What is the iron infusion like?
During an iron infusion, a healthcare professional will insert a small needle into a vein, typically in the arm or hand. They will then attach an IV bag filled with iron solution, which is slowly dripped into the bloodstream over a period of time, typically between 30 minutes to a few hours.
The infusion is typically performed in a medical setting such as a hospital, clinic, or infusion center, and the patient may be seated or lying down during the procedure. The patient may feel a slight pinch or discomfort when the needle is inserted, but this should only last a few seconds.
During the infusion, the patient may feel a sense of warmth or a metallic taste in the mouth. Some people may also experience mild side effects such as headache, nausea, or muscle aches, but these typically resolve on their own shortly after the infusion is completed.
After the infusion, the healthcare professional will monitor the patient for a short period of time to ensure there are no adverse reactions. Depending on the patient’s condition, they may need multiple iron infusions over a period of weeks or months to fully replenish their iron levels.
Is it serious if you need an iron infusion?
If a person has been diagnosed with iron deficiency anemia, it means that their body doesn’t have enough iron to produce sufficient hemoglobin, which can cause symptoms like fatigue, weakness, and shortness of breath. In some cases, iron deficiency anemia can be treated with dietary changes or oral iron formulations. However, if these treatments are not effective, an iron infusion may be recommended.
While the need for an iron infusion may sound concerning, it is a safe and effective treatment option for many people with iron deficiency anemia. Intravenous infusions of iron have evolved from a poorly effective and dangerous intervention to a safe cornerstone in the treatment of iron deficiency [5].’
Why would you need an intravenous iron infusion?
Iron infusion is usually recommended when a person has iron deficiency anemia, a condition in which the body doesn’t have enough iron to produce sufficient hemoglobin, the protein that carries oxygen in the blood. Some common reasons why a person may need an iron infusion include the following:
Inadequate iron absorption: Some medical conditions can impair the body’s ability to absorb iron from food, such as celiac disease, inflammatory bowel disease, or gastrointestinal surgery.
Chronic blood loss: Prolonged or heavy menstrual bleeding, bleeding from the gastrointestinal tract, or repeated blood donations can all result in chronic blood loss and subsequent iron deficiency.
Pregnancy: Pregnant women may require additional iron to support fetal growth and development and may develop iron deficiency anemia as a result.
Inability to tolerate oral iron supplements: Some people may experience digestive issues or other side effects from oral iron supplements, making an iron infusion a better option for them.
Non-responsive to oral iron therapy: Some people may not respond well to oral iron supplements or may require a more rapid increase in iron levels due to severe types of anemia or other medical conditions.
What are the benefits of an iron infusion?
Rapidly replenishing iron levels: Unlike oral iron supplements, which can take weeks or months to raise iron levels, iron infusions can provide a more rapid increase in iron levels. This can help alleviate symptoms of anemia, such as fatigue, weakness, and shortness of breath, more quickly.
Improved quality of life: By alleviating the symptoms of iron deficiency anemia, an iron infusion can improve a person’s overall quality of life. They may feel more energetic, be able to participate in daily activities more easily, and have an improved sense of well-being.
Avoiding the need for blood transfusions: In severe cases of iron deficiency anemia, a blood transfusion may be required to raise hemoglobin levels. However, an iron infusion may be a viable alternative to a blood transfusion, as it can also rapidly increase iron levels and avoid the need for a transfusion.
Fewer side effects: For some people, oral iron supplements can cause digestive issues such as nausea, constipation, or diarrhea. An iron infusion bypasses the digestive system and can reduce the likelihood of these side effects.
Convenience: Depending on the specific type of iron infusion used, the treatment may only need to be administered once or a few times over the course of several weeks or months, which can be more convenient than taking daily oral iron supplements.
What are the side effects of an iron infusion?
Like any medical treatment, iron infusions can have potential side effects, though they are usually mild and temporary. Some common side effects of iron infusion can include:
Headache
Nausea
Dizziness
Muscle or joint pain
Flushing or skin rash
Changes in taste
Fatigue
Low blood pressure
Swelling or inflammation at the injection site
In rare cases, more serious side effects can occur, such as:
Allergic reactions, including anaphylaxis, can be life-threatening
Infection at the injection site or in the blood
Fluid buildup in the lungs
High fever
It is important to note that the risk of serious side effects is low, and most people tolerate iron infusions well. However, it is important to discuss any concerns or questions with a healthcare professional and to follow their instructions for monitoring potential side effects.
People who have a history of allergies, asthma, or autoimmune disorders may have a higher risk of developing a reaction to an iron infusion. Healthcare professionals may monitor these individuals more closely during the infusion or may recommend alternative treatments.
What is the recovery period after an iron infusion?
The recovery period after an iron infusion can vary from person to person, but in general, most people can resume their normal activities shortly after the infusion. Some people may feel more energetic and have improved symptoms of anemia within a few days, while others may take longer to notice a difference.
In some cases, people may experience mild side effects after the infusion, but these usually resolve within a few days. It is important to report any persistent or severe symptoms to a healthcare professional promptly.
It is also important to continue monitoring iron levels and managing any underlying medical conditions that may contribute to iron deficiency anemia. This may involve follow-up blood tests, dietary changes, or additional treatments as recommended by a healthcare professional.
How long does an iron infusion stay in your body?
The duration that an iron infusion stays in the body can vary depending on a few factors, such as the specific type of iron infusion used and the individual’s body’s ability to absorb and utilize iron. In general, the effects of an iron infusion can last several weeks to several months, and the amount of time it stays in the body can vary from person to person.
Iron is gradually taken up by the body’s cells and used to produce new red blood cells, which can take several weeks or longer, depending on the individual’s rate of erythropoiesis. The body also has a natural mechanism for regulating iron absorption and utilization, which can help ensure that excess iron is eliminated from the body over time.
Iron infusion testing near me
MyconciergeMD offers the best iron infusion treatment near me in Beverly Hills but can also come to your home or office throughout the Los Angeles area. We serve patients near Beverly Hills, Bel Air, West Hollywood, Santa Monica, West Los Angeles, Culver City, Hollywood, Venice, Marina del Rey, Malibu, Manhattan Beach, Redondo Beach, Downtown Los Angeles, Encino, Woodland Hills, Sherman Oaks, Calabasas, Burbank, Glendale, Hidden Hills, Agoura Hills, Northridge, North Hollywood, Topanga, Canoga Park, Reseda, Valley Glen, Chatsworth, West Hills, Winnetka, Universal City, Silverlake, Echo Park, and many more.
References:
1. Koch TA, Myers J, Goodnough LT. Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations. Anemia. 2015;2015:1-10. doi:https://doi.org/10.1155/2015/763576
2. Macdougall IC. Intravenous iron therapy in patients with chronic kidney disease: recent evidence and future directions. Clinical Kidney Journal. 2017;10(suppl_1):i16-i24. doi:https://doi.org/10.1093/ckj/sfx043
3. Cançado RD, Muñoz M. Intravenous iron therapy: how far have we come?. Rev Bras Hematol Hemoter. 2011;33(6):461-469. doi:10.5581/1516-8484.20110123
4. Aung T, Coleman J, Davidson PW, Hetzel DJ, Aung ST. Intravenous iron infusion and newer non-dextran formulations. N Z Med J. 2021;134(1534):118-127. Published 2021 Apr 30.
5. Schaefer B, Meindl E, Wagner S, Tilg H, Zoller H. Intravenous iron supplementation therapy. Mol Aspects Med. 2020;75:100862. doi:10.1016/j.mam.2020.100862
Board Certified in Internal Medicine and Specialist in Concierge Medicine & Executive Health. Dr. Nazarian practices Integrative Medicine with focus on preventative medicine, anti-aging, hormone replacement therapy and IV Vitamin optimizations. Dr. David Nazarian, received his bachelor of sciences from the University of Los Angeles, California in Psychology and Biology. He obtained his Medical Doctorate degree from Sackler School of Medicine. He completed his medical residency at Huntington Memorial Hospital, a University of Southern California affiliate hospital. Once completed, he established a practice in the heart of Beverly Hills. Dr. Nazarian is a Diplomat of the American Board of Internal Medicine. He has received numerous awards and recognition as a top doctor in his field.
