Tirzepatide (Mounjaro): A Medical Breakthrough in Sustainable Weight Loss

Now Available at My Concierge MD

For millions of people, losing weight isn’t just about appearance—it’s a serious health concern tied to increased risks of heart disease, diabetes, inflammation, and decreased quality of life. And for many, diet and exercise alone simply aren’t enough. That’s why at My Concierge MD, we are proud to offer one of the most innovative, medically advanced solutions available today: Tirzepatide, also known by its brand name Mounjaro. Tirzepatide is indicated for adults with obesity or overweight who have weight related medical problems.

Tirzepatide is a powerful, FDA-approved, once-weekly injectable medication that has demonstrated significant success in treating obesity and related metabolic disorders. It is FDA-approved to treat adults with obesity or overweight, including those with severe obstructive sleep apnea and obstructive sleep apnea.

Clinical trials have shown that patients using Tirzepatide under proper medical supervision can lose up to 25% of their body weight—a result previously thought unachievable without surgical intervention. But this isn’t just about losing pounds. It’s about transforming your health from the inside out.

At My Concierge MD, we combine Tirzepatide therapy with comprehensive metabolic evaluations, customized weight loss planning, and ongoing physician-led support, ensuring your journey toward a healthier weight is safe, effective, and sustainable. Tirzepatide helps adults lose weight and improve health outcomes.

What Is Tirzepatide (Mounjaro), and How Does It Work?

Tirzepatide is a once-weekly injectable medication that belongs to a unique class of drugs called dual incretin receptor agonists. Specifically, tirzepatide is a dual GIP and GLP-1 receptor agonist, meaning it activates both the GIP and GLP-1 receptors to mimic the action of natural hormones.

A receptor agonist is a compound that binds to and activates specific hormone receptors in the body, triggering physiological responses. It acts on two key hormone pathways in the body: GLP-1 (Glucagon-like peptide-1) and GIP (Glucose-dependent insulinotropic polypeptide).

These naturally occurring hormones regulate appetite, food intake, glucose metabolism, and energy storage. By mimicking their effects, Tirzepatide essentially helps reset the body’s metabolic function.

GLP-1 has been used successfully in medications like semaglutide (Ozempic and Wegovy) for years. What makes Tirzepatide unique is that it also activates GIP receptors, offering an amplified effect on insulin sensitivity, appetite regulation, and fat burning.

As a 1 receptor agonist, tirzepatide enhances insulin release in response to meals, which improves blood sugar control in people with type 2 diabetes and obesity. Together, this dual mechanism helps patients feel fuller for longer, reduce cravings, eat less naturally, and burn stored fat more efficiently—all while supporting better blood sugar control and improving cardiometabolic health.

When comparing tirzepatide versus semaglutide, clinical studies have shown that tirzepatide, as a dual GIP and GLP-1 receptor agonist, may provide greater reductions in blood sugar and body weight than semaglutide, which is a GLP-1 receptor agonist alone. This difference in efficacy is attributed to tirzepatide’s dual mechanism of action.

This is not a temporary stimulant or crash diet pill. Tirzepatide helps your body work with you—not against you—by targeting the biological systems that control why we gain weight and why we struggle to lose it. One of the ways tirzepatide works is by slowing gastric emptying, which increases feelings of fullness and helps regulate appetite.

Over time, patients experience improved metabolic markers, lowered inflammation, better cholesterol profiles, and of course, substantial fat loss.

Tirzepatide is administered as a subcutaneous injection, typically given once a week in the abdomen, thigh, or upper arm.

A Closer Look at How Tirzepatide Regulates Metabolism and Appetite

The beauty of Tirzepatide lies in its precision targeting of metabolic dysfunction. Many people gain weight not because they lack willpower but because their hormonal signals have been disrupted—by insulin resistance, chronic stress, poor sleep, inflammation, or aging. This leads to a vicious cycle of elevated blood sugar, increased fat storage, and frequent hunger signals that sabotage traditional diet attempts.

Tirzepatide interrupts that cycle at a hormonal level. It:

• Slows gastric emptying, which keeps you full longer and reduces meal sizes.
• Enhances insulin secretion in response to glucose, keeping blood sugar more stable and preventing energy crashes.
• Suppresses glucagon, the hormone that tells your liver to release stored sugar—thus reducing unnecessary fat storage.
• Reduces food-related dopamine spikes, which helps limit emotional or reward-based eating.
• Decreases appetite, a common effect that contributes to weight loss and is frequently observed alongside other gastrointestinal side effects.

Monitoring weight changes is an important part of therapy, as fluctuations can indicate the efficacy of tirzepatide in reducing body weight.

This multifaceted mechanism makes Tirzepatide one of the most powerful tools we have today to treat obesity at its biological root, with proven benefits in reducing body weight, rather than just managing the symptoms. When paired with professional guidance, it’s not only effective but transformative.

Tirzepatide is part of a new generation of agonist medications for metabolic disease, offering innovative options for patients seeking better outcomes.

Tirzepatide Dosing: Tailored to Your Body, Supervised by Experts

Treatment initiation with tirzepatide is an important step, and therapy should always begin at a low dose to minimize side effects and allow your body to adjust.

Tirzepatide is available in several injectable formulations ranging from 2.5 mg to 15 mg, allowing us to gradually and safely titrate your dose to match your body’s needs and tolerance. These dosage forms include convenient single dose pens and single dose vials, making administration straightforward and supporting treatment adherence.

At My Concierge MD, we don’t take a one-size-fits-all approach. We start by thoroughly evaluating your medical history, current medications, lab work, and lifestyle. Based on that, we initiate treatment at the lowest dose—2.5 mg once weekly—and gradually increase every 4 weeks, if tolerated.

Each 0.5 mL dose is equivalent to 50 units. For compounded forms:

• 25 units = 2.5 mg
• 50 units = 5.0 mg
• 100 units = 10.0 mg, and so on

Standard dosage progression chart for Tirzepatide:

The current dose is used as a reference point to guide titration, with increases made every four weeks based on your response and tolerance. The maximum dose approved for tirzepatide is 15 mg once weekly.

Doses are injected subcutaneously (under the skin) once a week—into the abdomen, thigh, or upper arm. Injections can be done at any time of day, with or without food. We guide you step-by-step through proper administration, including how to rotate injection sites and how to recognize the injection clicks (indicating full delivery of the medication).

It is important to monitor for injection site reactions, such as redness, swelling, or discomfort at the injection site, and report any concerns to your healthcare provider.

What If You Miss a Tirzepatide Dose?

Sticking to your regular dosing schedule is key to achieving the best results with Tirzepatide, both for weight reduction and blood sugar management. If you realize you’ve missed a dose, take it as soon as you remember—unless your next scheduled dose is less than four days away. In that case, simply skip the missed dose and continue with your regular dosing schedule. Never take two doses within three days of each other, as this can increase the risk of side effects.

If you’re ever unsure about what to do after a missed dose, reach out to your healthcare provider for personalized advice. Consistency is important for optimal results, so setting reminders or using a medication tracker can help you stay on track.

Interactions with Other Medications: What You Need to Know

Tirzepatide can interact with a variety of prescription medicines, so it’s important to keep your healthcare provider informed about everything you’re taking. If you use insulin or other diabetes medicines like sulfonylureas, combining them with tirzepatide may increase your risk of low blood sugar.

Your provider may need to adjust your dosages or monitor your blood sugar more closely to keep you safe. Additionally, tirzepatide may reduce the effectiveness of birth control pills, so you may need to use an alternative method of birth control while on this medication.

Always share a complete list of your medications, including over-the-counter drugs, supplements, and vitamins, to help your provider prevent unwanted interactions and ensure your treatment is as effective as possible.

Warnings and Contraindications: Is Tirzepatide Safe for You?

While tirzepatide offers powerful benefits for weight management and glycemic control, it’s not suitable for everyone. You should not use tirzepatide if you have a personal or family history of medullary thyroid cancer or multiple endocrine neoplasia syndrome type 2, as it may increase the risk of thyroid cancer.

Serious allergic reactions, including anaphylaxis and angioedema, have been reported—so if you’ve ever had an allergic reaction to tirzepatide or any of its ingredients, this medication is not recommended. Use caution if you have a history of severe stomach problems, such as acute pancreatitis, or diabetic retinopathy, as tirzepatide may worsen these conditions.

Women who are pregnant, planning to become pregnant, or breastfeeding should avoid tirzepatide, as it may harm an unborn baby. Always discuss your full medical history and any concerns with your healthcare provider before starting tirzepatide to ensure it’s the safest choice for you.

What Weight Loss Results Can You Expect?

Clinical studies of Tirzepatide have been nothing short of groundbreaking. These results are based on large clinical trials and systematic reviews, which have demonstrated that, on average, patients lost 15–22.5% of their body weight over a 72-week period.

Many people began noticing appetite suppression and changes in food cravings within just 1–2 days of their first injection. Weight loss typically begins within the first month, with visible body composition changes—especially around the abdomen and hips—within 6–8 weeks.

In addition to weight loss, patients often see improvements in:

• Insulin sensitivity and A1C levels
• Blood pressure and lipid profiles
• Liver health (reduction in fatty liver indicators)
• Mental clarity, mood, and self-confidence
• Diabetes care and primary care management, including better glycemic control and integration into comprehensive diabetes care plans

By addressing the underlying metabolic drivers of weight gain, Tirzepatide provides long-term, sustainable change—not just temporary weight loss.

As part of ongoing care, it is important to monitor for kidney disease and gallbladder problems, as these have been noted in clinical trials and should be considered during treatment.

Are There Any Side Effects or Serious Allergic Reactions?

Like all medications, Tirzepatide may cause side effects, especially during the early phases as your body adjusts. However, most are mild and transient. The most commonly reported symptoms include:

• Nausea
• Bloating
• Fatigue
• Diarrhea or constipation
• Mild abdominal discomfort
• Indigestion (dyspepsia)

In addition to these common side effects, some patients may experience adverse events such as abdominal pain or, rarely, acute kidney injury, particularly if dehydration occurs due to gastrointestinal symptoms.

These symptoms usually subside within a few weeks and can often be minimized through dose titration and lifestyle support. At My Concierge MD, we stay in close communication with every patient, making adjustments as needed and offering supportive care to manage discomfort if it arises. Your safety is our top priority.

We do not recommend Tirzepatide for patients with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2, due to rare but potential risks. Other rare but serious risks include hypersensitivity reactions (such as severe allergic responses or angioedema), severe pain, trouble swallowing, blurred vision, and low blood sugar levels.

If you experience any of these symptoms, contact your healthcare provider immediately. Your eligibility will always be thoroughly reviewed before starting treatment.

If you are scheduled for surgery or any procedure involving anesthesia or deep sedation, inform your healthcare provider that you are taking Tirzepatide, as this may affect your risk of complications.

Is Tirzepatide Right for You?

Tirzepatide is an excellent option for individuals who:

• Have a BMI of 30 or greater (classified as obese), or
• Have a BMI of 27+ with weight-related health conditions such as PCOS, type 2 diabetes, insulin resistance, hypertension, or fatty liver
• Need to treat moderate to severe obstructive sleep apnea (OSA) in adults with obesity, as tirzepatide is FDA-approved for this indication
• Have tried and struggled with traditional methods like calorie restriction, cardio programs, or trendy diets—without success

This medication is not just for cosmetic weight loss. It is for people whose quality of life, energy, and health are being compromised by excess weight. Tirzepatide has also been shown to help reduce upper stomach fat and improve body composition. If you’re ready to commit to long-term change—and want expert support every step of the way—Tirzepatide may be the key you’ve been missing.

Cost and Availability: Making Tirzepatide Accessible

The cost of tirzepatide can vary based on your insurance plan, pharmacy, and location. Eli Lilly, the manufacturer, offers patient assistance programs and savings cards to help make this innovative weight loss medication more affordable.

Some pharmacies may also provide discounts or special pricing on single dose vials and single dose pens, which are available in a range of strengths to match your prescribed dose.

To find the best option for your needs, talk with your healthcare provider, insurance company, and local pharmacy. They can help you navigate coverage, explore savings opportunities, and select the right dosage form to support your weight loss and glucose control goals.

With the right support, tirzepatide can be a more accessible part of your journey to better health.

Why Choose My Concierge MD for Tirzepatide Treatment?

At My Concierge MD, we believe true weight loss success happens when science meets personalized care. Our team of board-certified physicians and medical specialists doesn’t just prescribe a drug—we build a plan that revolves around your unique metabolism, lifestyle, and long-term health goals.

Comprehensive Medical Evaluation

Before initiating treatment, we perform a full health screening to assess your current metabolic function, lab values, medication interactions, and underlying conditions. This ensures that Tirzepatide is not only effective—but safe—for your body.

Ongoing Monitoring and Adjustments

We track your progress closely using advanced metrics like body fat percentage, muscle mass, visceral fat levels, and blood biomarkers. We make proactive dosage adjustments and provide tailored recommendations to enhance results at every stage of the journey.

Expert-Led Care by Dr. David Nazarian

Our practice is led by Dr. Nazarian, a Board-Certified Internal Medicine Physician with a specialized focus in Concierge and Preventative Medicine. With years of experience in integrative health, hormone optimization, and medical weight management, Dr. Nazarian and his team deliver safe, results-driven care.

Frequently Asked Questions (FAQs)

How quickly will I start losing weight with Tirzepatide?
Most patients begin noticing reduced hunger within 1–2 days, with measurable weight loss often starting in week 3 or 4.

How much weight can I expect to lose overall?
Clinical trials show average weight loss of 15–25% over a 12–18 month period, depending on your starting weight, dosage, and commitment to lifestyle changes.

Can I take Tirzepatide if I have other health conditions?
That depends on your individual health profile. We evaluate all patients thoroughly to ensure the medication will not interact with existing treatments or conditions.

Do I still need to follow a healthy diet?
Yes. While Tirzepatide reduces appetite, long-term success depends on lifestyle changes, including a balanced diet, regular movement, and sleep hygiene.

Ready to Take the First Step? We’re Here to Help.

If you’re ready to finally see results—without extreme dieting or risky surgery—Tirzepatide may be the right solution for you. At My Concierge MD, we’ll guide you through the process from start to finish, ensuring you get the most from this revolutionary medication.

Don’t wait for change. Start your transformation today.
Call now or schedule a consultation with Dr. Nazarian and take the first step toward long-term, medically guided weight loss.