Epitalon peptide – Beverly Hills, Los Angeles

At Conceirge MD,we offer epitalon peptide as part of our anti-aging and wellness services. Our team of medical professionals can help determine if this supplement is right for you and create a personalized plan to incorporate it into your overall circadian rhythm.

The basic function of epitalon is to stimulate the natural production of telomerase, a natural enzyme that helps cells replicate telomeres, which are the protecting sections of our DNA. This permits our DNA to replicate, allowing our bodies to produce new cells and rejuvenate existing ones. Younger folks have more telomerase and longer telomeres. The longer the telomere strands, the greater cell health, and replication they provide. However, as humans age, their telomerase production declines, and as a result, cell replication and health suffer. This is the primary cause of increasing human lifespan.

What is epitalon?

Epitalon is a four-amino acid peptide made up of alanine, glutamic acid, aspartic acid, and glycine. It works by increasing the production of telomerase, an enzyme responsible for the length of our telomeres. Telomeres are the protective caps on our chromosomes that shorten as we age, leading to cellular damage and, eventually, cell death. Epitalon is considered the “fountain of youth” synthetic peptide and has been studied for over 35 years. The primary function of epitalon in the pineal gland of the brain is to increase the natural production of a specific enzyme. This enzyme is responsible for replicating the protective parts of our DNA.

Additionally, Epithalon promotes a natural and healthy sleep cycle while making sure cortisol and other stress hormones are not raised throughout the day. This is critical as these hormones remaining high can lead to excess abdominal weight gain.

The AEDG peptide (Ala-Glu-Asp-Gly, Epitalon) has been demonstrated to affect the function of the pineal gland, retina, and brain. AEDG peptide prolongs animal life and reduces experimental cancerogenesis. In retinal and human periodontal ligament stem cells, AEDG peptide stimulates neuronal cell development. The study’s goal was to look into the effect of AEDG peptide on neurogenic differentiation gene expression and protein synthesis in human gingival mesenchymal stem cells and to propose an epigenetic mechanism for this process.

What does epitalon do to the skin?

While epitalon is well known for its anti-aging properties on a cellular level, it can also help to rejuvenate skin health. Our skin loses suppleness and grows thinner as we age, resulting in wrinkles and sagging. Epitalon has been demonstrated to stimulate collagen formation, which can aid in skin firmness and the appearance of fine lines and wrinkles. Furthermore, epitalon may aid in UV protection and encourage faster healing of injured skin cells. It is crucial to note that while epitalon may have certain skin benefits, it should not be used in place of good skincare habits such as wearing sunscreen and exercising adequate cleanliness.

Dr. Vladimir Khavinson‘s research from Russia found that epithalon can activate skin fibroblasts, which are responsible for repairing and maintaining the extracellular matrix that keeps our skin robust. Collagen, elastin, and other important skin proteins can be found in the extracellular matrix of the skin. Epithalon stimulates fibroblasts and increases their quantity by 30-45% in rats, according to clinical studies.

Collagen strengthening is one of the various ways that skin aging lotions claim to work. While these creams perform well in the lab, their capacity to permeate the skin and influence collagen is occasionally limited. This suggests that the creams work, but their effects are only temporary. It’s a different story from Epithalon.

Epithalon actually enters the cells and stimulates the growth and development of fibroblasts, which secrete proteins such as collagen. This has a considerably more profound effect, resulting in skin regeneration on several levels.

What are the potential benefits of Epitalon?

Here are some of the potential advantages of Epitalon :

Can Help You Sleep Better

Epitalon affects the pineal gland, which produces melatonin, a hormone that helps regulate sleep. It can help you fall and stay asleep faster by increasing the synthesis of this hormone.

Decreased Risk Of Cancer

Although the epitalon‘s usefulness against cancer is still being tested in animal models, the results are encouraging for people. In one study, epithalon therapy increased lymph flow and increased targeted cell death (apoptosis), a process that slows the growth of cancerous cells, in rats with colon cancer. Additionally, it reduced the largest tumor size in mice with breast tumors. According to a different study, mice given epitalon had no metastasizing. To put it another way, the cancer never metastasized to another area of the body.

The synthetic pineal peptide Epitalon (Ala-Glu-Asp-Gly) was investigated for its ability to inhibit spontaneous carcinogenesis in mice. Female C3H/He mice that were one year old were housed in regular settings for 6.5 months. Epitalon was injected five times a week at a dose of 0.1 microg. Small doses of Epitalon taken over an extended period of time had no harmful effects. The number of tumor-bearing mice with malignant tumors was reduced after treatment with Epitalon, and metastases were also avoided.

An Effective Antioxidation Agent

Antioxidants eliminate harmful chemicals known as free radicals, which have been related to a variety of age-related diseases, including Parkinson’s and Alzheimer’s. A rat study discovered that epithalamin boosted overall antioxidant capacity by 36%.

Improves Eyesight

Epitalon has been shown to boost the production of melatonin, which helps to protect the eyes from blue light damage.

We investigated the effect of the tetrapeptide Epitalon (Ala-Glu-Asp-Gly) on the progression of congenital pigmented retinal degeneration. The use of Epitalon in Campbell rats has been shown to increase the bioelectric and functional activity of the retina by preserving its morphological structure. In 90% of cases, epitalon therapy produces a beneficial therapeutic impact in patients with degenerative retinal diseases. The examination of Epitalon effects reveals that the tetrapeptide engages in transcription pathways shared by the epiphysis and retina.

Immune System Booster

Epitalon has been demonstrated in studies to strengthen the immune system by raising the production of T-cells, which are white blood cells that play an important part in fighting infections and disorders.

What are the side effects of epitalon?

When taking epitalon, some people may feel moderate headaches or dizziness, while others may notice changes in appetite or sleep patterns. It’s also possible to have modest gastrointestinal problems, such as nausea or diarrhea. It’s crucial to note that these adverse effects are usually modest and temporary.

What are the side effects of epitalon

Does epitalon increase testosterone?

There is insufficient evidence to declare for certain. It is critical to understand that epitalon is not a hormone, but rather a synthetic peptide that mimics the effects of the natural hormone epithalamine. As a result, it may indirectly affect testosterone levels by promoting the health and function of the pituitary gland, which regulates hormone synthesis.

Epitalon was created to restore reproductive function in aged rats by boosting testosterone levels in the male blood and re-establishing the female estrus cycle. Melatonin has also been found to preserve mitochondrial functioning in vitro during oocyte aging . Based on the biological effects of peptide bioregulators, we anticipated that Epitalon could lower oxidative stress in aged oocytes while also improving oocyte quality.

Epitalon Peptide near me

My Concierge, MD, Beverly Hills, offers the best Epitalon Peptides near me in Beverly Hills but can also come to your home or office throughout the Los Angeles area. We serve patients near Beverly Hills, Bel Air, West Hollywood, Santa Monica, West Los Angeles, Culver City, Hollywood, Venice, Marina del Rey, Malibu, Manhattan Beach, Redondo Beach, Downtown Los Angeles, Encino, Woodland Hills, Sherman Oaks, Calabasas, Burbank, Glendale, Hidden Hills, Agoura Hills, Northridge, North Hollywood, Topanga, Canoga Park, Reseda, Valley Glen, Chatsworth, West Hills, Winnetka, Universal City, Silverlake, Echo Park, and many more.

References

1. Khavinson V, Diomede F, Mironova E, et al. AEDG Peptide (Epitalon) Stimulates Gene Expression and Protein Synthesis during Neurogenesis: Possible Epigenetic Mechanism. Molecules. 2020;25(3):609. doi:https://doi.org/10.3390/molecules25030609

2. E. Epithalon and Skin Rejuvenation. PeptideSciences.com. Published August 17, 2022. Accessed May 12, 2023. https://www.peptidesciences.com/blog/epithalon-and-skin-rejuvenation

3. Kossoy G;Anisimov VN;Ben-Hur H;Kossoy N;Zusman I. Effect of the synthetic pineal peptide epitalon on spontaneous carcinogenesis in female C3H/He mice. In vivo (Athens, Greece). 2021;20(2). Accessed May 12, 2023. https://pubmed.ncbi.nlm.nih.gov/16634527/

4. Khavinson V;Razumovsky M;Trofimova S;Grigorian R;Razumovskaya A. Pineal-regulating tetrapeptide epitalon improves eye retina condition in retinitis pigmentosa. Neuro endocrinology letters. 2021;23(4). Accessed May 12, 2023. https://pubmed.ncbi.nlm.nih.gov/12195242/

5. Yue X, Liu SL, Guo JN, et al. Epitalon protects against post-ovulatory aging-related damage of mouse oocytes in vitro. Aging. 2022;14(7):3191-3202. doi:https://doi.org/10.18632/aging.204007

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