Bpc 157 peptide

At My Concierge MD, we offer BPC peptide therapy for those interested in trying this revolutionary treatment. Contact us today to learn more about this exciting new therapy and how it can improve your overall health and well-being.

BPC 157 is growing in popularity as a supplement for treating various illnesses only in the US. And for a good reason—BPC 157 is swiftly becoming one of the most popular health supplements available thanks to its advantages.

BPC has long been utilized in the medical field, but it has only lately started to be sold as a supplement to the general public. It would be silly to ignore the numerous advantages that this health supplement offers.

A synthetic variant of the naturally occurring protein known as the Body Protection Compound (BPC) peptide is called the BPC-157 peptide. It is an amino acid chain that has been demonstrated to encourage healing and regeneration in the body. The BPC-157 peptide‘s history begins with the discovery of the compound by a Croatian scientific team in the early 1990s. Since then, the therapeutic potential of the BPC-157 peptide has been thoroughly investigated.

BPC is a peptide that is produced from a protective protein that has been used to boost collagen formation, encourage muscle and ligament regeneration, and prevent gastric ulcers. While eosinophilic esophagitis, inflammatory bowel disease, and inflamed intestinal epithelium are among the stomach and intestinal conditions that BPC-157 is frequently used to treat, it is also a potent peptide for wound healing and general regeneration after damage due to its capacity to improve type 1 collagen and increase blood flow via angiogenesis. Notably, BPC-157 helps folks who want to increase joint mobility, treat previous injuries, and relieve joint pain.

We examined the pleiotropic positive effects of the stable gastric pentadecapeptide BPC 157, three very recent demonstrations that may be crucial in the function of the gut-brain and brain-gut axis, and therapeutic use in the treatment of central nervous system illnesses, in particular. First, when administered after reperfusion, BPC 157 prevented bilateral common carotid artery clamping-induced stroke in rats and reversed memory loss, poor coordination, and neuronal damage.

What is the chemical structure of BPC 157?

The chemical structure of BPC consists of a sequence of 15 amino acids with a molecular weight of 1419.53552 g/mol. It is classified as a pentadecapeptide, meaning it is composed of 15 amino acids.

Although the FDA has not approved BPC peptide for human use, it has gained popularity in the bodybuilding and athletic communities due to its reported benefits.

The essential active portion of the BPC peptide in human gastric juice is the pentadecapeptide body protection compound (BPC)157, having the amino acid sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val (Sikiric et al., 1993). BPC157 has been shown to have an obvious protective effect on the acute and chronic damage of the esophagus, stomach, duodenum, and colorectal mucosa caused by a variety of factors (Veljaca et al., 1995; Sikiric et al., 1994, 1999a, 2000a; Bilic et al., 2001; Jelovac et al., 1999; Duzel et al., 2017).

What are the benefits of BPC 157?

This peptide is thought to have a beneficial impact on the body’s natural healing processes. Some potential advantages of BPC-157 include the following:

Encourages Brain Health

BPC-157 can mend brain tissue and neurons, which allows it to have healing effects on the brain as well. In fact, research has revealed that BPC-157 not only helps treat other different central nervous system illnesses but can even prevent severe brain injuries. The peptide may also be able to lessen the symptoms of hypoglycemia, seizures, and brain lesions.

BPC 157 regimens (10.0 g, 10.0 ng/kg i.p.) revealed a significant attenuation of damage with a better early outcome and little postponed mortality throughout a 24 h post-injury period after an induced traumatic brain injury (TBI) in mice by a falling weight. Finally, the traumatic lesions (subarachnoidal and intraventricular hemorrhage, brain laceration, hemorrhagic laceration) were less severe, and the subsequent cerebral edema had reduced significantly.

Enhances Wound Healing

Body healing properties make up the majority of BPC-157‘s reputation. In fact, scientific research has shown that it helps to speed up the healing of a variety of tissues, including skin burns, muscle, bone, ligament, and tendon. The peptide‘s capacity to stimulate the body’s growth hormone receptors and boost blood flow to the wounded area is the reason for this. Athletes, as well as a regular individual who experiences chronic pain or past injuries, might benefit greatly from BPC-157‘s remarkable therapeutic abilities.

In order to better understand its effects, gastric pentadecapeptide BPC 157 was given to burned mice either topically or systemically. This substance is known to improve wound or fracture healing, as well as a number of models of gastrointestinal diseases. On the backs of mice, controlled burning was used to inflict deep partial skin thickness burns (1.51.5 cm) that covered 20% of the total body area. Gastric lesions were then measured 1, 2, 3, 7, 14, and 21 days after the injury. BPC 157 was used for the first time right after burning and then once every day until 24 hours before sacrifice.

Gut Health and Ulcers

Gut health is critical to all bodily functioning. There are numerous causes of poor gut health, including alcoholism, antibiotic use, stress, sugary meals, and frequent use of NSAIDs such as ibuprofen.

Fortunately, BPC-157 can help mend the gut lining and reduce edema, which can help treat gastrointestinal disorders associated with poor gut health. The peptide may be especially beneficial for patients suffering from leaky gut syndrome, Crohn’s disease, or irritable bowel syndrome.

According to research, Injections of BPC 157 aided in the healing of stomach ulcers in rats. It also protected the rats’ intestines from toxicity like alcohol and aided in the healing of gastrointestinal fistulas, which are irregular openings in the digestive tract that allow fluids to flow. BPC 157 injections decreased inflammation in rats with stomach ulcers and arthritis in one study.

The peptide also lowered inflammation in rats with an irritated esophagus (the tube that connects the throat to the stomach). Interestingly, BPC 157 may function on the gut-brain axis, assisting in the “from the inside out” relaxation of the stress response.

Promotes tissue healing

It has been discovered that BPC-157 Peptide is an effective tissue healing promoter. Its usefulness in treating a variety of injuries, including tendon and ligament sprains and increasing bone repair in osteoporosis, has been supported by numerous research. BPC-157 functions by boosting angiogenesis, the generation of new blood vessels, and growth factor synthesis. The anti-inflammatory capabilities of this peptide have also been demonstrated, decreasing inflammation in the wounded area and encouraging tissue regeneration. A neuroprotective quality.

After the rat’s Achilles tendon was severed from the calcaneal bone, drugs [BPC 157 (10 g, 10 ng, 10 pg), 6-methylprednisolone (1 mg), 0.9% NaCl (5 mL)] were administered. Were given alone or in combination [kg body weight (b.w.) intraperitoneally, once daily, first 30-min after surgery, last 24 h before analysis]. BPC 157 improves healing functionally [Achilles functional index (AFI) values significantly increased], biomechanically (load to failure, stiffness, and Young elasticity modulus significantly increased), macro/microscopically, immunohistochemistry (better organization of collagen fibers, and advanced vascular appearance, more collagen type I).

What are the side effects of BPC 157?

There are various negative consequences associated with peptides used to promote muscle mass. Although there isn’t enough information to predict with certainty whether BPC 157 will result in the same outcomes, some of the negative effects linked to peptide consumption include the following:

• Liver and kidney damage
• uncharacteristic hunger and weight gain
• Is it hot or cold?
• Depending on the peptide, blood pressure fluctuates (increases or decreases).
• Heart issues such as irregular rhythms
• Cancer
• Dizziness and weariness
• Potential risk to fetuses

While the BPC-157 peptide shows great promise as a treatment option for various injuries and conditions, more research is needed to fully understand its mechanisms of action and potential benefits and risks. As with any new treatment option, it should be used under the guidance of a healthcare professional.

BPC 157 Peptide Near Me

My Concierge, MD, Beverly Hills, offers the best bpc 157 peptides near me in Beverly Hills but can also come to your home or office throughout the Los Angeles area. We serve patients near Beverly Hills, Bel Air, West Hollywood, Santa Monica, West Los Angeles, Culver City, Hollywood, Venice, Marina del Rey, Malibu, Manhattan Beach, Redondo Beach, Downtown Los Angeles, Encino, Woodland Hills, Sherman Oaks, Calabasas, Burbank, Glendale, Hidden Hills, Agoura Hills, Northridge, North Hollywood, Topanga, Canoga Park, Reseda, Valley Glen, Chatsworth, West Hills, Winnetka, Universal City, Silverlake, Echo Park, and many more.

References

1. Jakša Vukojević, Marija Milavić, Darko Perović, et al. Pentadecapeptide BPC 157 and the central nervous system. 2022;17(3):482-482. doi:https://doi.org/10.4103/1673-5374.320969

2. Xu C, Sun L, Ren F, et al. Preclinical safety evaluation of body protective compound-157, a potential drug for treating various wounds. 2020;114:104665-104665. doi:https://doi.org/10.1016/j.yrtph.2020.104665

3. Tudor M, Jandric I, Marovic A, et al. Traumatic brain injury in mice and pentadecapeptide BPC 157 effect. 2010;160(1-3):26-32. doi:https://doi.org/10.1016/j.regpep.2009.11.012

4. Mikus D, P Sikiric, Sven Seiwerth, et al. Pentadecapeptide BPC 157 cream improves burn-wound healing and attenuates burn-gastric lesions in mice. 2001;27(8):817-827. doi:https://doi.org/10.1016/s0305-4179(01)00055-9

5. Andrija Krivić, Tomislav Anic, Sven Seiwerth, Dubravko Huljev, Predrag Sikiric. Achilles Detachment in Rat and Stable Gastric Pentadecapeptide BPC 157: Promoted Tendon-to-Bone Healing and Opposed Corticosteroid Aggravation. 2006;24(5):982-989. doi:https://doi.org/10.1002/jor.20096