Thymosin Beta-4

What’s Thymosin Beta-4, and how does it help your body? If you are having trouble understanding how this peptide works and its benefits, keep on reading. For further questions and treatment inquiries, visit our My Concierge MD page.

What is Thymosin Beta-4?

Thymosin Beta-4, also known as TB-500, is a small, endogenous peptide comprising 43 amino acids originally isolated from the Thymus gland. It comes from the ‘Thymosin’ family of lymphocyte growth factors and is found in the thymus gland, spleen, and peritoneal macrophages.

How does Thymosin Beta-4 work?

TB-500 primarily upregulates actin, a cell-building protein that plays a crucial role in cell structure, movement, and tissue repair. By enhancing actin production, TB-500 promotes tissue regeneration, wound healing, and overall cellular health.

What are the potential benefits of Thymosin Beta-4?

Wound Healing and Recovery:

Thymosin Beta-4 plays a pivotal role in wound healing. It aids in the recovery process after injuries, making it a valuable peptide for bodybuilders and athletes. Promoting angiogenesis helps form new blood vessels, facilitating tissue repair and regeneration.

Enhanced Stamina and Endurance:

Athletes and fitness enthusiasts can rejoice! Thymosin Beta-4 not only heals wounds but also enhances stamina, strength, and endurance. When bruises or wounds threaten progress, this peptide steps in to accelerate recovery and keep you on track.

Corneal Health:

Thymosin Beta-4 benefits corneal health. It contributes to maintaining the integrity of the protective outer layer of the eye.

Cardiovascular Recovery:

After a heart attack or myocardial infarction (MI), Thymosin Beta-4 aids in quick recovery.

Side Effects of Thymosin Beta-4 work

• Head Rush
• Lethargy/FatigueNausea: Occasional stomach discomfort.
• Headache
• Skin Irritation
• Possible Energy Crash

Cost of Thymosin Beta-4

• Thymosin Beta-4 2mg: $250
• Thymosin Beta-4 5mg: $300
• Thymosin Beta-4 10mg vial: $349

Are there any known drug interactions with Thymosin Beta-4?

Thymosin Beta-4, a fascinating peptide, appears to be quite well-tolerated. Fortunately, no adverse drug interactions have been observed. Additionally, the side effects are minimal—typically limited to some irritation or burning sensation at the site of injection

How long does it take to see the results of Thymosin Beta-4?

The timeline for seeing results can vary based on the specific condition and individual response.

• For tissue repair and healing, a typical recommended dosage range for Tβ4 is between 2-2.5 mg per week, divided into multiple smaller injections.
• Eye drops containing Tβ4 have been studied for corneal health, with evaluations at Day 1, 7, 14, 21, 28 (End of Treatment), and 56 (follow-up).
• When using Tβ4, a common safe dose range is 300 micrograms to 1 gram per day, often administered in cycles of 6 weeks on and 6 weeks off.

Can TB-500 be used for muscle growth or athletic performance enhancement?

Studies have shown that TB-500 can enhance muscle hypertrophy, leading to increased muscle mass and strength. Its effect is believed to be linked to its ability to promote the growth of new blood vessels, which enhances nutrient delivery to muscle cells and supports their growth

Fact-Based Effectivenesses of Thymosin Beta-4

A study with Mdx mice was conducted to investigate the effects of Thymosin Beta-4. The mice were treated with the peptide over 6 months with exercises to induce muscle pathology. The treated mice showed an increase in skeletal muscle regenerating fiber [1].

Another study stated that Thymosin Beta-4 helps repair tissue and heal nerves and may help treat myocardial infarction, stroke, and various nerve injuries [2].

A 2010 report stated that local treatment with Thymosin Beta-4 (Tβ4) enhances wound healing with minimal scarring, improves collagen organization, and reduces myofibroblast presence. This leads to less scarring and stronger tissue repair [3].

A study explored the use of Thymosin Beta-4 eye drops for severe dry eye in nine human participants. After 56 days of treatment, the group receiving the eye drops experienced a 35% decrease in eye discomfort and a 59% improvement in dry eye testing parameters [4].

Another study examined venous ulcers, which occur when blood doesn’t flow well and usually appear on the lower leg. It studied 73 people and found that using a 0.03% synthetic thymosin-beta 4 helped wounds heal faster, leading to full healing in 25% of patients within three months [5].

Thymosin Beta-4 Near Me

My Concierge MD offers the best Thymosin Beta-4 near me in Beverly Hills but can also come to your home or office throughout the Los Angeles area. We serve patients near Beverly Hills, Bel Air, West Hollywood, Santa Monica, West Los Angeles, Culver City, Hollywood, Venice, Marina del Rey, Malibu, Manhattan Beach, Redondo Beach, Downtown Los Angeles, Encino, Woodland Hills, Sherman Oaks, Calabasas, Burbank, Glendale, Hidden Hills, Agoura Hills, Northridge, North Hollywood, Topanga, Canoga Park, Reseda, Valley Glen, Chatsworth, West Hills, Winnetka, Universal City, Silverlake, Echo Park, and many more.

References:

1. Spurney CF, Cha HJ, Sali A, et al. Evaluation of skeletal and cardiac muscle function after chronic administration of thymosin beta-4 in the dystrophin deficient mouse. PLoS One. 2010;5(1):e8976. Published 2010 Jan 29. doi:10.1371/journal.pone.0008976
2. Bjørklund G, Dadar M, Aaseth J, Chirumbolo S. Thymosin β4: A Multi-Faceted Tissue Repair Stimulating Protein in Heart Injury. Curr Med Chem. 2020;27(37):6294-6305. doi: 10.2174/0929867326666190716125456. PMID: 31333080.
3. Ehrlich HP, Hazard SW 3rd. Thymosin beta4 enhances repair by organizing connective tissue and preventing the appearance of myofibroblasts. Ann N Y Acad Sci. 2010 Apr;1194:118-24. doi: 10.1111/j.1749-6632.2010.05483.x. PMID: 20536458.
4. Sosne G, Dunn SP, Kim C. Thymosin β4 significantly improves signs and symptoms of severe dry eye in a phase 2 randomized trial. Cornea. 2015 May;34(5):491-6. doi: 10.1097/ICO.0000000000000379. PMID: 25826322.
5. Guarnera G, DeRosa A, Camerini R; 8 European sites. The effect of thymosin treatment of venous ulcers. Ann N Y Acad Sci. 2010 Apr;1194:207-12. doi: 10.1111/j.1749-6632.2010.05490.x. PMID: 20536470.